Effect of superhelical structure on the secondary structure of DNA rings.

نویسندگان

  • D Glaubiger
  • J E Hearst
چکیده

A quantity, called the linking number, is defined, which specifies the total number of t,wists in a circular helix. The linking number is invariant under continuous deformations of the ring and therefore enables one to calculate the influence of superhelical structures on the secondary helix of a circular molecule. The linking number can be determined by projecting the helix into a plane and counting strand crosses in the projection as described. For example, it has been shown that for each 180" twist in a left-handed superhelix, a right-handed 360" twist is removed from the secondary helix, thus allowing local unwinding.

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عنوان ژورنال:
  • Biopolymers

دوره 5 8  شماره 

صفحات  -

تاریخ انتشار 1967